The GFAP MIP Biosensor is a highly selective, ultra-sensitive electrochemical sensor designed for rapid detection of glial fibrillary acidic protein (GFAP)—a key biomarker of traumatic brain injury (TBI), concussion, and neurological damage.
Using Fluidome’s molecularly imprinted polymer (MIP) technology, this biosensor provides antibody-like specificity while offering superior stability, reproducibility, and cost-effectiveness.
The GFAP sensor integrates seamlessly with electrochemical readout systems and can be paired with microfluidic cartridges for automated sample-to-answer workflows.
Detection can be performed directly from blood, serum, or plasma with minimal sample preparation.
Key Features
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Ultrasensitive detection with a limit of detection (LOD) of 0.02 pg/mL
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Wide linear detection range: 0.02 pg/mL – 200 ng/mL
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Rapid 5–10 minute assay time
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High specificity using a tailor-made MIP “plastic antibody”
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Compatible with blood, serum, and plasma
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Reusable or disposable formats
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High batch-to-batch reproducibility (CV <5%)
- Stable performance under proper storage conditions
Applications
- Validated and published research applications include:
- Detection of GFAP in TBI and concussion models
- Quantification of neuroinjury biomarkers
- Preclinical neurological research
- Method development in biosensing and electrochemical analysis
- Microfluidic POC research
- High-throughput biomarker screening
- Assay development for decentralized neurodiagnostics (RUO)
Packaging and Specifications
Packaging material: Polypropylene tube or microfluidic cartridge
Sterility: Not sterilized
Packaging: 1 biosensor per package
Format options: Electrode-only / integrated microfluidic chip
Assay time: 5–10 minutes
Technology: MIP-based electrochemical biosensor
Transduction: SWV, CV, EIS compatible
LOD: 0.02 pg/mL
Linear range: 0.02 pg/mL – 200 ng/mL
Sample types: Blood, serum, plasma
Stability: >90% signal retention after 4 weeks
Reproducibility: Coefficient of variation (CV) < 5%
Shipping conditions: Room temperature
Recommended storage: 4°C (short-term) or refrigeration (long-term)
Regulatory status: Research Use Only (RUO)—not for diagnostic use
Analytical Performance
Evidence from multiple studies demonstrates:
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High selectivity for GFAP over interfering proteins
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87% reduction in variability with integrated QC strategy
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Excellent reproducibility (RSD 1.44% with QC process)
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Stable over 60 days in refrigerator/vacuum storage
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Robust performance across repeated uses (optional reusable format)
Technical Note
A high-affinity MIP-based electrochemical biosensor enabling ultrasensitive, rapid, and reproducible quantification of GFAP in blood-derived samples. Designed for research into neurotrauma, neurodegeneration, and biomarker discovery.
Important Notes
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The GFAP Biosensor is a Research Use Only tool and is not validated for clinical diagnosis.
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Bulk orders and multi-analyte bundles are available.
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Custom microfluidic integration or cartridge design is available upon request.
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Please contact us for bulk pricing, quotations, or distributor inquiries.
