Cortisol MIP Biosensor (RUO)
The Cortisol MIP Biosensor is a highly selective, ultra-sensitive electrochemical sensor designed for rapid quantification of cortisol, the primary stress hormone involved in metabolic regulation, immune response, circadian rhythm, and physiological stress pathways.
Built using Fluidome’s proprietary molecularly imprinted polymer (MIP) technology, this biosensor replaces fragile antibody- or enzyme-based assays with a stable synthetic “plastic antibody,” providing robust performance in complex biofluids such as sweat.
The cortisol sensor integrates easily with standard electrochemical readout systems and is fully compatible with microfluidic cartridges for automated sample-to-answer workflows.
validated performance includes direct detection from sweat, supporting stress monitoring, wearable platform development, and biological research applications.
Key Features
-
Ultrasensitive detection with a limit of detection (LOD) of 0.1 ng/mL
-
Rapid 5–10 minute assay time
-
High specificity using tailor-made MIP binding sites
-
Validated for use with sweat samples
-
Compatible with microfluidic integration
-
Electrode-only or MIP-Chip formats available
-
High reproducibility and long-term stability
-
Excellent signal consistency across fabrication batches
Applications
Published and validated applications include:
-
Quantitative cortisol detection in sweat
-
Stress biomarker monitoring
-
Wearable biosensor and patch-based detection system
-
Endocrine and metabolic research
-
Human performance, circadian rhythm, and exercise physiology studies
-
Lab-on-chip and microfluidic POC assay development
-
Method development in electrochemical biosensing (RUO)
Packaging and Specifications
Packaging material: Polypropylene tube or microfluidic cartridge
Sterility: Not sterilized
Packaging: 1 biosensor per package
Format options: Electrode-only / integrated microfluidic chip
Assay time: 5–10 minutes
Technology: MIP-based electrochemical biosensor
Transduction: SWV, CV, EIS compatible
LOD: 0.1 ng/mL
Sample types: Sweat
Linear detection: (Validated via calibration curves provided in technical note)
Stability: Maintains performance under proper refrigerated storage
Reproducibility: High repeatability (supported by data from cortisol MIP calibration curves)
Shipping conditions: Room temperature
Recommended storage: 4°C (short-term) or refrigeration (long-term)
Regulatory status: Research Use Only (RUO) — not for diagnostic use
Analytical Performance
Based on technical note data:
-
Strong linearity across physiologically relevant cortisol concentrations
-
Clear square-wave voltammetric response with increasing cortisol spike levels
-
High selectivity for cortisol against structurally similar steroid hormones
-
Stable signal after long-term refrigerated storage
-
Robust performance in sweat—no requirement for complex preprocessing
-
Reliable target rebinding at the MIP surface with excellent sensitivity
Technical Note
A robust MIP-based electrochemical biosensor enabling rapid and sensitive cortisol detection directly from sweat. Designed for stress physiology, wearable technology development, endocrine research, and biofluid-based biosensing applications.
Important Notes
The Cortisol MIP Biosensor is Research Use Only (RUO) and not validated for clinical diagnosis.
Bulk orders and multi-analyte packs (e.g., cortisol + lactate + succinate) are available.
Custom microfluidic or wearable integration can be requested.
Contact us for bulk pricing, quotations, OEM integration, or distributor inquiries
