Application Spotlight:
Fluidome’s Metabolite Standard Mix in Biosensor Development
Expanding Applications: Fluidome’s Metabolite Standard Mix in Biosensor Development
Originally designed to support high-precision LC-MS-based metabolomics workflows, the Metabolite Standard Mix by Fluidome is now finding broader utility in the field of biosensor development. Researchers are increasingly adopting this standardized mix to evaluate matrix effects and support the analytical performance assessment of emerging biosensing technologies.
Why Biosensors Need Standardization
Biosensors are gaining traction across medicine, diagnostics, environmental monitoring, and biotechnology. However, one of the persistent challenges in biosensor development is ensuring consistent analytical performance — especially when sensors are exposed to complex biological matrices such as plasma, serum, or urine.
Matrix components can interfere with signal output, affecting sensor sensitivity, selectivity, linearity, and overall reliability. To address this, researchers require reproducible and quantitative reference materials that simulate real sample conditions — and that’s where Fluidome’s metabolite mix comes in.
A Mix Built for Metabolomics — and Perfect for Sensors
The Metabolite Standard Mix by Fluidome contains a broad range of compounds spanning multiple metabolite classes, including amino acids, organic acids, sugars, and more. Each component is included at biologically relevant concentrations and precisely quantified to support robust method development and benchmarking.
While its primary use is in LC-MS-based metabolomics, researchers developing biosensors are now leveraging this mix to:
Assess matrix effects on sensor signal and performance
Evaluate sensor behavior under complex, physiologically relevant conditions
Benchmark performance across different matrices or sensor platforms
This makes the mix particularly valuable for validating multiplexed biosensors and sensors targeting key metabolic markers such as glucose, lactate, and amino acids.
Flexibility Through Dry Format
One of the most cited advantages of Fluidome’s mix is its dry format. Unlike liquid standards that degrade quickly or require cold-chain logistics, the dry formulation offers unmatched flexibility:
Reconstitute when needed — no rush against stability timelines
Use any solvent or matrix — from buffer to serum or synthetic fluids
Adjust to any concentration — match your assay or calibration range
This flexibility makes it easy for biosensor developers to integrate the mix into various testing workflows and adapt to project-specific needs.
Supporting the Future of Biosensing
We’re proud to see the Metabolite Standard Mix by Fluidome supporting innovation well beyond its original application. As the biosensor field continues to grow, we’re committed to providing reliable standards that enable faster, more reproducible sensor development and validation.
Publications Using Fluidome’s Mix for Biosensor Development
Several recent studies have successfully employed our mix to assess matrix effects and support biosensor validation:
https://shorturl.at/fYaWb
- https://shorturl.at/536Pu
https://shorturl.at/AeN5f
Are you working on a biosensor project? Contact us to learn how Fluidome’s metabolite standards can support your research and development pipeline.
