Infection Diagnostics

 The mortality rate of Bloodstream Infection (BSI) increases by 8% for each hour the antibiotic treatment is delayed, and those patients who receive the wrong antibiotic over this period, face a ten-fold increase in mortality. Also, rapid analyzing blood samples for bacterial resistance is also a critical step in reducing the mortality risk posed by a BSI. On the other hand, established clinical bioassays to isolate and detect bacteria and perform antibiotic susceptibility testing (AST) are cost-intensive, tedious and need a large amount of sample volume (10–30 mL), and are time-consuming, typically requiring 3-5 day. To address this challenge, we developed an Infection Diagnostic Plate (IDP) coupled with mass spectrometry for rapid antibiotic susceptibility testing. An infection diagnostic plate (IDP) is an integral part of the workflow, allowing for the incubation and sampling of the patient samples in one step.

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